Noah lives with his wife Naameh and sons Shem, Ham and Japheth. One night, Noah experiences a vision of a devastating flood. A visit to the mountainous lair of Noah's grandfather Methuselah confirms the dire prediction.
Blu is a domesticated blue macaw, who lives with his owner and best friend Linda in Moose Lake, Minnesota. When Linda learns about another rare blue macaw in Rio de Janeiro, she and Blu head to exotic Brazil to track down the bird called Jewel.
Neurotic blue macaw Blu and Jewel are settled with three children in Rio. She worries that their brood is too domesticated and insists the entire family answers the call of the wild and flies to the Amazon.